Although glomerular capillary C4d deposition is a sensitive marker of classic complement pathway activation, it is not a sensitive marker for active lupus nephritis. However, C4d staining intensity did not correlate with the lupus nephritis activity index. Moreover, the intensity of C4d deposits correlated with those of capillary IgG, IgA, C4, C1q, and fibrinogen deposits. CINEMA 4D is a robust, professional, easy to use 3D Animation software that offers customizable configuration suitable for any industry and all skill levels. In eight cases, C4d deposition was found in the absence of capillary or mesangial C4 deposits. The CINEMA 4D product family has everything to satisfy your professional 3D modeling, texturing, animating and rendering needs. Immunofluorescence for C4d showed diffusely granular staining along glomerular capillary loops, in all cases examined (1+, in 8 cases 2+, in 7 cases 3+, in 6cases). The presence and intensity of glomerular C4d deposition were compared with the corresponding histologic activity index for each case. Mean patient age was 29.3 +/- 13.5 years (range: 7-55 years). Twenty-one patients diagnosed as having lupus nephritis (WHO class III: 4 cases IV: 12 cases V: 5 cases) were included. Abstract This study was designed to evaluate whether glomerular C4d deposition may be a useful marker of lupus nephritis activity.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |